The Interreg IPA South Adriatic is a cross-border cooperation Programme co-funded by the European Union through the Instrument for Pre-Accession (IPA III), with a total budget of 81.258.768,19 euro (including 17,51% co-financing). It widely builds on the results of the Interreg IPA CBC Italy-Albania-Montenegro programme 2014-2020.

The programme is managed by Puglia Region, which participates together with another Italian Region, Molise; Albania and Montenegro participate with the entire territory.